Dr. B. DINESH KUMAR,Scientist ‘G’ & HoD,
Doctorate in Pharmacology (faculty of medicine), serving at FDTRC, NIN for over 32 yrs in various capacities. As a Pharmacologist associated in establishing State-of-Art facility at Centre for Advanced Research for Preclinical Toxicology (PCT) established in 1999 by ICMR at NIN with team of other scientists.
Areas of work: i. Preclinical safety / efficacy evaluation of Biopharmaceuticals, GMOs, etc., ii. Social Drug Epidemiology, iii. Detection of early Lead toxicity & prevention.
Key contributions: In the recent past, a challenging work has been undertaken for the first time in the country on preclinical safety evaluation of indigenously developed Recombinants, r-DNA anti rabies, Human Papilloma Vaccine (HPV), innovative therapies (Human Adult Mesenchymal Stem Cells (MSCS),GMOs for which there are no defined regulatory guidelines. Among the other screened products -Interferon, Japanese Encephalitis & Tetravalent Vaccine, Traditional Ayurvedic formulations & Bhasmas (Herbo-minerals), other foods and food additives etc. The above activity is ongoing at PCT which has become a self sustained & successful model of Public-Public, Public-Private Partnership Collaborative Centre of ICMR. More than 45 different products have been screened and 20 of them are translated in clinical use or in clinical trial.
Developed two educations films: i) Promotion of Rational Drug use ii. Prevention of Lead Toxicity in addition to other scientific activities.
Expert Committee Member: i. Developing guidelines for pre /clinical trials in ASU Drugs, ii. Drafting the guidelines for Accreditation of Ethics Committee, Clinical Trial Sites and Investigators for MoH& FW, GOI., rules for financial compensation in the case of trial related injury or death. Norman Borlaug fellow, GLP Trainer for South East Asian Countries (WHO-TDR), National President- Indian Pharmacological Society (2014-2016).