Scientist ‘E’ 
Lipid Chemistry Division

Contact:  +91-40-27197472

Brief Profile

After receiving her Ph.D. in the area of Molecular & Cellular Biology from University of Hyderabad in 2006, she pursued postdoctoral research work at the Department of Pharmacology, University of Cambridge, UK (2006 – 2008) in the area of intracellular calcium signalling and calcium channels. She carried out further postdoctoral research at the Division of Diabetes, Endocrinology and Metabolism, Imperial College London, UK on wide range of research activities starting from pancreatic β cell insulin secretion, glucose homeostasis, functional genomics of various mutations associated with early and late onset diabetes. Dr. Gargi joined ICMR Head Qtrs as Assistant Editor (Scientist ‘D’) of Indian Journal of Medical Research (IJMR), which is a peer-reviewed, international, monthly journal published by ICMR. During her tenure IJMR brought out several Special issues on important topics like smokeless tobacco, nutrition research, antimicrobial resistance surveillance system, cancer etc. In May 2016, she has moved to ICMR-NIN, Hyderabad and currently working as ScE in the Lipid Chemistry division. Her current research interests include early childhood growth and development, healthy gut microbiota for healthy metabolism, breastfeeding on infant gut flora. She is also involved in metabolomic studies on type 2 diabetes in urban thin and poor and glucose metabolism, and metagenomic studies looking into antimicrobial resistance transmission through gut microbial community. She is conducting several extramural and intramural research projects and keen on collaborative efforts in these areas.

Publications [Total 28; Total citation 1162; h-index 19; i10-index 22 (Google scholar)]
  1. Surekha M V*, Suneetha N, Balakrishna N, Putcha UK, Satyanarayana K, Geddam JJB, Sreenu P, Tulja B, Mamidi RS, Rutter GA, Meur G.Impact of COVID-19 during pregnancy on placental pathology, maternal and neonatal outcome - A cross-sectional study on anemic term pregnant women from a tertiary care hospital in southern India. Front Endocrinol (Lausanne). 2023;14:1092104. doi:10.3389/fendo.2023.1092104
  2. Anindya R, Rutter GA, Meur G. New-onset type 1 diabetes and severe acute respiratory syndrome coronavirus 2 infection. Immunol Cell Biol. 2023;101(3):191-203. doi:10.1111/imcb.12615
  3. Mamidi RS, Banjara SK, Manchala S, Babu CK, Geddam JJB, Boiroju NK, Varanasi B, Neeraja G, Reddy GVR, Ramalakshmi BA, Hemalatha R, Meur G. Maternal Nutrition, Body Composition and Gestational Weight Gain on Low Birth Weight and Small for Gestational Age-A Cohort Study in an Indian Urban Slum. Child (Basel, Switzerland). 2022;9(10). doi:10.3390/children9101460
  4. Meur G, et al. Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention. Diabetes 2010; 59 (3):653-61.
  5. Noordeen NA, Meur G, et al. Glucose-induced nuclear shuttling of ChREBP is mediated by Sorcin and Ca2+ ions in pancreatic β-cells. Diabetes 2012; 61 (3):574-85.
  6. Meur G, et al. Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6). J Biol Chem 2011; 286 (15):3647-56.
  7. Meur G, et al. Targeting and retention of type 1 ryanodine receptors to the endoplasmic reticulum. J Biol Chem 2007; 282(32):23096-103.
  8. Solomou A, Meur G, et al. The Zinc Transporter Slc30a8/ZnT8 Is Required in aSubpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion. J Biol Chem 2015; 290(35):21432-42.
  9. Bellomo EA, Meur G, Rutter GA. Glucose regulates free cytosolic Zn2+ concentration, Slc39 (ZiP) and metallothionein gene expression in primary pancreatic islet beta-cells. J Biol Chem 2011; 286(29):25778-89.
  10. Rosker C, Meur G, et al. Functional ryanodine receptors in the plasma membrane of RINm5F pancreatic beta-cells. J Biol Chem 2009; 284(8):5186-94. (Commentary in Islets, 1, 82-84).
  11. Mitchell RK, Hu M, Chabosseau PL, Cane MC, Meur G, et al. Molecular Genetic Regulation ofSlc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance. Mol Endocrinol 2016; 30 (1):77-91.
  12. Seillier M, Pouyet L, N’guessan P, Nollet M, Capo F, Peyta L, Varrault A, Bertrand, G Guillaumond F, Meur G, et al. Tumor Protein 53-Induced Nuclear Protein 1 prevents metabolic syndrome by regulating mitochondrial-elicited oxidative stress and lipid metabolism. EMBO Mol Med 2015; pii: e201404318.
  13. Chabosseau P, Tuncay E, Meur G, et al. Mitochondrial and ER-targeted eCALWY probes reveal high levels of free Zn2+. ACS Chem Biol 2014; 9 (9):2111-20.
  14. Gerber PA, BellomoEA, Hodson DJ, Meur G, et al. Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+in pancreatic beta cells. Diabetologia 2014; 57 (8):1635-44.


Awards and Honors

EASD Travel grant to attend 47th EASD Annual Meeting at Stockholm; Twice qualified CSIR-UGC-NET-JRF for PhD (2000, 2002), ICAR-JRF for MSc (1998-2000).