Scientist-G & Head 
Food Safety

Contact:  91-40-27197405

Brief Profile

Dr Sinha contributed to the field of analytical toxicology and his innovative contributions have been implicated in fields with wide scientific, medical and policy implications.  He developed a new tissue schizontocidal and gametcytocidal drug (6-methoxy-5,8 di-(4’-amini-1’-methyl butylamino quinoline) which is more active and less toxic than primaquine for treatment of Malaria. He established health risk assessment for fixing Maximum Residue Limit of pesticides in carbonated beverages (1ppb). This was adopted by the Joint Parliament Committee, Government of India to monitor pesticide residues in ingredients like sugar, thereby ensuring better standards and promoting exports contributing to the country’s economy. He developed a new biomarker (1-napthol) for estimation of acetyl cholinesterase enzyme and toxicants for measuring exposure to organophosphates and its effect which are crucial for the prognosis in real time to save lives of exposed victims. He reported Adefovir dipivoxil is a potent anti-viral drug for treatment of infested dengue viruses. He received prestigious Shakuntala Amirchand Award (ICMR) and international fellowships from ICMR &DHR, India and WHO. He has a patent to his credit. He worked in Toxicology Department, CDC Atlanta and was a visiting Professor at college of Medicine, Cincinnati University, USA. He honed degree in toxicology at OPCW Netherlands.

  1. Vakdevi Validandi, Arjun L Khandare, Srinivas Dheeravath, Sureka Mullapudi Venkata, Srinivasu Kurella, Sukesh Narayan Sinha, Nutritional, biochemical, and histopathological study on dose and time dependent effects in fluoride exposed rats. Fluoride 56 (4 Pt 2):428-448 October-December 2023
  2. Kumar D, Sinha SN*, Vasudev K. Development and Validation of a New UFLC–MS/MS Method for the Detection of Organophosphate Pesticide Metabolites in Urine. Molecules. 2023 Aug 1;28(15):5800
  3. Kumar D, Sinha SN*, Rajendra S, Sharma K. Assessing farmer's exposure to pesticides and the risk for non-communicable diseases: A biomonitoring study. Science of The Total Environment. 2023 May 26:164429.
  4. Gandla V, Chiluka M, Gupta H, Sinha SN, Chakraborty P. Sediment-water partitioning and risk assessment of organochlorine pesticides along the urban, peri-urban and rural transects of Krishna River Basin, Peninsular India. Science of The Total Environment. 2023 May 20; 874:162360.
  5. Chougule PR, Sangaraju R, Patil PB, Qadri SS, Panpatil VV, Ghosh S, Mungamuri SK, Bhanoori M, Sinha SN*. Effect of ethyl gallate and propyl gallate on dextran sulfate sodium (DSS)-induced ulcerative colitis in C57BL/6 J mice: preventive and protective. Inflammopharmacology. 2023 Jun 2:1-8.
  6. Ramakrishna Ungarala , Sukesh Narayan Sinha* , R Shyam Sunder , Ultra high-Performance Liquid Chromatography (UHPLC) method development and validation for the identification of oxidized product of Epigallocatechin-3-Gallate (EGCG), Journal of Chromatographic Science (JCS) , 2022, 00(3):1-11
  7. Ramakrishna Ungarala, Manne Munikumar, Sukesh Narayan Sinha*, Dileshwar Kumar, R Shyam Sunder and Suresh Challa, Assessment of antioxidant, immunomodulatory activity of oxidized Epigallocatechin-3-Gallate (Green Tea Polyphenol) and its action on Main protease of SARS-CoV-2 – An in vitro and in silico approach, Antioxidants 2022, 11(2), 294
  8. Balaji Gouda , Sukesh Narayan Sinha*, Meram Chalamaiah , Validandi Vakdevi , Patangay Shashikala ,Bantal Veeresh , Venkata Mullapudi Surekha , Vasudev Kasturi and Naveen Kumar Boiroju.Sex Differences in AnimalModels of Sodium-Valproate-Induced Autism in Postnatal BALB/cMice: Whole-Brain Histoarchitecture and 5-HT2A Receptor Biomarker Evidence. Biology 2022, 11, 79.
  9. Epidemiological Investigation of an Acute Neurological Outbreak in Eluru,India, Mummadi MK, Pandurangi R, Geddam JJB, Sinha Sukesh Narayan*, Rajendran A, P. S, et al. Investigation of an acute neurological outbreak in Eluru, India, 2020. PLoS ONE 16(11): e0259192, (2021)
  10. Human Placental Mesenchymal Stem Cell Therapy Restores the Cytokine Efflux and Insulin Signaling in the Skeletal Muscle of Obesity-induced Type 2 Diabetes Rat model. Kotikalapudi Nagasuryaprasad, Sukesh Narayan Sinha , Ramesh R. Bhonde, Sathish Kumar Mungamuri, Vijayalakshmi Venkatesan* Hum Cell. 2022, 35(2):557-571.
  11. G. Balaji, Sukesh Naryan Sinha*, M.V. Surekha, V. Kasturi, S.K. Mungamuri and P. Shashikala, Correlation studies on pathological changes in brain with neurotransmitters and behavioural changes in Balb/c mice , J. Environ. Biol., 43, 43-51 (2022).,
  12. Kotikalapudi Nagasuryaprasad, Samuel Joshua Pragasam, Sukesh Narayan Sinha, Ramesh R.Bhonde, Nemani Harishanker, Sathish Kumar Mungamuri, Vijayalakshmi Venkatesan..The promise(s) of Mesenchymal Stem Cell Therapy in averting Preclinical Diabetes – Lessons from in vivo and in vitro model systems, scientific reports, Scientific Reports volume 11, Article number: 16983 (2021)
  13. Sukesh Naryan Sinha*, K.R. Kumar, R. Ungarala et al., Toxicokinetic analysis of commonly used pesticides using data on acute poisoning cases from Hyderabad, South India, Chemosphere, Volume 268, April 2021, 129488 129488
  14. Sinha SN*, Ramakrishna UV, Sinha PK, Thakur CP (2020) A recurring disease outbreak following litchi fruit consumption among children in Muzaffarpur, Bihar—A comprehensive investigation on factors of toxicity. PLoS ONE 15(12): e0244798.
  15. Sathish Kumar Mungamuri , Sukesh Narayan Sinha , and Yamini Javvadi, Understanding the Alterations in Lipid Metabolism in NAFLD Progression: Currents Trends and Future Directions, Critical ReviewsTM in Oncogenesis,Cite Score;3 26(1):35–49 (2021)
  16. A simple and sensitive liquid chromatography–tandem mass spectrometry method for quantification of multi-residual pesticides in blood, separation science plus, Dileshwar Kumar, Sukesh Narayan Sinha*, Ramakrishna Ungarala Sathish Kumar Mungamuri Vasudev Kasturi, 5 (5), 2022, 1-14, DOI:
  17. Sinha SN*, Ungarala R, Kumar D, Sangaraju R, Kumar S (2022) A novel RP-HPLC method for quantification of cholinesterase activity in human blood: An application for assessing organophosphate and carbamate insecticide exposure. PLoS ONE 17(12): e0279287. https://
  18. Kumar, K. R., & Sinha, S. N*. (2022). A review of the clinical management of current organophosphate poisoning treatments in humans. International Journal of Health Sciences, 6(S9), 2394–2415.
  19. Placental Mesenchymal Stem Cells Restores Glucose and Energy Homeostasis in Obesogenic Adipocytes By: Nagasuryaprasad Kotikalapudi; Samuel Joshua Pragasam Sampath; Sukesh Narayan Sinha; R Bhonde; Sathish Kumar Mungamuri; vijayalakshmi Venkatesan Cell and Tissue Research 2022 Oct 13. doi: 10.1007/s00441-022-03693-y
  20. Investigation of acute organophosphate poisoning in humans based on sociodemographic and role of neurotransmitters with survival study in South India, Sukesh Narayan Sinha*, Rajesh Kumar Kumpati, Pandu Naik Ramavath, Rajendra Sangaraju, Balaji Gouda & a. Priyanka Chougule, Scientific Reports volume 12, Article number: 16513 (2022)
  21. Balaji, G., Sangaraju, R., Sinha, Sukesh. Narayan*., & Shashikala, P. (2022). Identification and characterization of Ethyl gallate from Ethyl acetate fraction of Phyllanthus emblica fruit, and invitro free radical scavenging activity. International Journal of Health Sciences, 2022, 6(S8), 2390–2400.
  22. Ramakrishna U. V.1, Shyam Sunder R.2, Rajesh Kumar K.1, Sukesh Narayan Sinha1*. Method Development and Validation for rapid identification of Epigallocatechin Gallate using Ultra-High-Performance Liquid Chromatography, DOI: 10.1371/journal.pone.0227569, PLOS ONE, 2020, 15 (1), e0227569.
  23. Sukesh Narayan Sinha, Air Pollution from Solid Fuels 2nd edition Encyclopedia of Environmental Health. Elsevier, vol. 1, pp. 49–60., ISBN: 9780444639516, 2019
  24. Ashwini V. Izankar, Aniket P. Sarkate, Pramod S. Patil, Arjun L. Khandare, S. N. Sinha, Kshipra S. Karnik, Yogesh W. More and Dattatraya N. Pansare Simple chromium catalyzed oxidative synthesis of quinazolinones and benzoxazinones from 2- aminobenzamide and anthranilic acid with arylaldehydes. Eur. Chem. Bull., 2019, 8(6) 180-187
  25. Shwari A.Kale, Nilema S. Gore, Aniket P. Sarkate, Bhagwan K. Sakhale, Arjun L. Khadare, S.N. Sinha, Kshipra S. Karnik, Dattatraya N. Pansare, Peel Extract Associated Oxidative Green Dakin Synthesis of Some Phenols using Aqueous Banana Extract Catalyst, Eur. Chem. Bull. 2019 8(5), 160-163
  26. G Balaji & SN Sinha*. Autism spectrum disorder (ASD): A current review of assessment,risk factors and prevention. Indian Journal of Biochemistry & Biophysics, 2018, 55 (375-383)
  27. Sukesh Narayan Sinha*, Venkat Reddy Banda, Correlation of Pesticide Exposure from Dietary Intake and bio-monitoring: The different sex and socio-economic study of children, Ecotoxicology and Environmental Safety 162 (2018) 170–177
  28. Venkat Reddy Banda , Shyam Perugu , Rajesh Kumar K. and Sukesh Narayan Sinha *,in-silico studies on human reproductive hormones and interactions with organophosphate, European Journal of Biomedical and Pharmaceutical sciences Volume: 5 Issue: 4 592-597: 2018 .
  29. M. Noor Ahmed, Sukesh Narayan Sinha* , Sudershan Rao Vemula, P. Sivaperumal, K.Vasudev,Shaik Ashu, Vishnu Vardhana Rao Mendu, V. Bhatnagar, Accumulation of polychlorinated biphenyls in fish and assessment of dietary exposure: a study in Hyderabad City, India, Environmental Monitoring and Assessment, February 2016, 188:94.
  30. Sukesh Narayan Sinha*, Paritosh K. Kar, Shyam Perugu, U.V. RamaKrishna, C.P. Thakur, Adefovir dipivoxil—A possible regimen for the treatment of dengue virus (DENV) infection, Chemometrics and Intelligent Laboratory Systems 155 (2016) 120–127
  31. UV Ramakrishna, Sukesh Narayan Sinha*, Neelam Kumari, Vijay Bhatnagar.(2014 July1). A Review on Pharmacognistic, Phytochemical, Chemical Profile and Apoptosis Induction in Yeast Cells of Guazuma Ulmifolia. Pharmanest,5(3),2130-2141.
  32. Shakeel Zaidi, Vijay Bhatnagar, Ashwin Bhai Patel, Somnath Tripathi, Sukesh Narayan Sinha*, Ranjana Choudhari, Vijay Shivgotra, (2015) Neurobehavioral, biochemical and immunological manifestations in workers exposed to organophosphate insecticides, IJBB, Vol.52(5&6), 305-310 .
  33. Ramakrishna U. V, Shyam Perugu, Sukesh Narayan Sinha*,  , Drug-Repositioning Of the Gallate Group from Egcg for the Repurposing, ejpmr, 2016, 3(7) , 253-262
  34. New Mathematical Formulas for Calculation of ATP Yield Due to The Complete Oxidation of Different Type of Fatty acids. Banda Venkat Reddy,  Bommena Rajendra prasad, Sukesh Narayan Sinha*,  , Noor Ahmed, Indian Journal of Biochemistry Biophysics, Vol.51, February 2014, pp. 52-57.
  35. RamaKrishna U.V, Dinesh Kumar B Sukesh Narayan Sinha*, Ratna Priya, Phytochemical Screening and polyphenol estimation by hplc of terminalia  arjuna. International Journal of Research in Pharmacology & Pharmacotherapeutics, volume-2, issue 3, 2013, ISSN 2278-2656.
  36. Sukesh Narayan Sinha*,  , VK Dua, H Venkatakrishna-Bhat, Infrared Spectroscopic Studies of Some Oxidative Products of Primaquine, International Journal of Chemistry, 2013 ISSN 2306-6415.
  37. Agatha Betsy, Sudershan Rao Vemula, Sukesh Narayan Sinha,  , Vishnu Vardhana Rao Mendu, Kalpagam Polasa, Assessment of dietary intakes of nineteen pesticide residues among five socioeconomic sections of Hyderabad—a total diet study approach, Environmental Monitoring and Assessment. 2013 1573-2959.
  38. Puppala Muthenna, Ganugula Raghu, Chandrasekhar Akileshwari, Sukesh Narayana Sinha, Palla Suryanarayana, Geereddy Bhanuprakash Reddy* Inhibition of Protein Glycation by Procyanidin-B2 Enriched Fraction of Cinnamon: Delay of Diabetic Cataract in Rats, International Union of Biochemistry and Molecular Biology. 2013, 941-950.
  39. Sukesh Narayan Sinha*,K. Vasudev , M. Vishnu Vardhana Rao, Quantification of organophosphate insecticides and herbicides in vegetable samples using the ‘‘Quick Easy Cheap Effective Rugged and Safe’’ (QuEChERS) method and a high-performance liquid chromatography–electrospray ionisation–mass spectrometry (LC–MS/MS) technique, Food Chemistry 132 (2012) 1574–1584 
  40. Sukesh Narayan Sinha*,  , M. Vishnu Vardhana Rao, K. Vasudev, Martins Odetokun, A liquid chromatography mass spectrometry-based method to measure organophosphorous insecticide, herbicide and non-organophosphorous pesticide in grape and apple samples, Food Control 25 (2012) 636-646.
  41. Sukesh Narayan Sinha*,  , M. Vishnu Vardhana Rao, K. Vasudev, Distribution of pesticides in different commonly used vegetables from Hyderabad, India, Food Research International 45 (2012) 161–169
  42. Sukesh Narayan Sinha*,  , V. K. Shivgotra, Environmental Monitoring of adulterated gasoline with kerosene and their assessment at exhaust level, Journal of Environmental Biology, 2012, 33, 729-734
  43. Sukesh Narayan Sinha*,  ,   Liquid Chromatography Mass Spectrometer (LC-MS/MS) Study of Distribution Patterns of Base Peak Ions and Reaction Mechanism with Quantification of Pesticides in Drinking Water Using a Lyophilization Technique, American Journal of Analytical Chemistry, 2011, 2 (5), 511-521.
  44. Sukesh Narayan Sinha*, K. Vasudev, M. Vishnuvardhana Rao, Martins Odetokun Quantification of organophosphate insecticides in drinking water in urban areasusing lyophilization and high-performance liquid chromatography–electrosprayionization-mass spectrometry techniques, International Journal of Mass Spectrometry 300 (2011) 12–20
  45. Sukesh Narayan Sinha*, V.K. Bhatnagar,   G. S. Tuteja, N. P. Agnihotri, R. L. Kalra,  A novel method for pesticides analysis in refined sugar samples using GC-MS/MS and solvent extraction method, Food chemistry, 126 (2011), 379-386.
  46. Sukesh Narayan Sinha*, Effect of dissociation energy: Signal to noise ratio on ion formation and sensitivity of analytical method for quantification and confirmation of triazofos in blood samples using gas chromatography–mass spectrometer (GC–MS/MS), International Journal of Mass Spectrometry 296 (2010) 47–52.
  47. Sukesh Narayan Sinha*, N.M. Desai, G.M. Patel, M.MMansuri and V. Shivgotra Concentration of nitrite in respirable particulate matter of ambient air in Vadodara, Gujarat, India J. Environ. Biol. 31, 375-378, 2010
  48. Sukesh Narayan Sinha*, and Zaidi, S.S.A. Gachromatography - Mass spectral analysis of paint thinner. Asian J Chem 20 (2008) 6365.
Total number of books and book chapters : 02

1. Sukesh Narayan Sinha*, and Nag, P.K. Air pollution from solid fuels. In: Nriagu JO (Ed.) (Elsevier) encyclopedia of Environmental Health 1 (2011) 46-52.

2. Sukesh Narayan Sinha*,  and V. K. Bhatnagar, Analysis of Toxicants by Gas Chromatography in Advanced Gas Chromatography – Progress in Agricultural, Biomedical and Industrial Applications (book), chapter-7, page 134-150, publisher InTech Europe, University Campus STeP Ri Slavka Krautzeka 83/A51000 Rijeka, Croatia

Awards and Honors

1. Fellow of National Academy of Medical Sciences (FAMS) 2023.

2. Fellow of the Royal Society of Chemistry (FRSC), London,U.K 2023.

3. Shakuntala Amir Chand Prize, 2004 ,Indian Council of Medical Research

4. Indian Council of Medical Research International Fellow  2008

5. Department of Health Research International Fellow 2015

6. WHO In-Country-Fellow 2008

7. Guest Researcher- ship  by Center of Decease of Control, Atlanta, USA, in 2008-2009

8. Visiting Professor by Cincinnati University, USA in 2015-2016

9. Head of the Delegates’ at 5th session of the Codex Committee on Contaminants in Food, held at The Den Hague, Netherlands in 2011.

10. Life member National Academy of Science, Allahabad

11. Expert member of joint FAO/WHO food standards programme codex committee on contaminants in foods sixth session, Maastricht, the Netherlands, 26 – 30 march 2012

12. Dua, V.K., Sinha, S.N., Sharma, V. P., New Tissue Schizontocidal and Gametcytocidal drug in the treatment of Malaria, Patent no. 189970 in the Gazette of India, Part—III Section 2 dated 24. 5. 03.

13. Analytical skill development course from University of Helsinki, Finland in 2006

14. Certificate of Course Mastery, Safety Survival Skills Pt1 from USA (CDC, Atlanta) in 2008

15. EDITORIAL BOARD: SciMedicine Journal

16. Best Innovation award by Indian Council of medical Research (ICMR), 2022 for new innovative research work June 23. 2023

  • 1. Frontier Chemistry Editor on Special Issue